Basavapathruni, A.: search on Z-Library

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1

Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases

Eisuke Murakami, Aravind Basavapathruni, William D. Bradley, Karen S. Anderson

Journal:

Antiviral Research

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

2

Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L

Basavapathruni, Aravind, Jin, Lei, Daigle, Scott R., Majer, Christina R. A., Therkelsen, Carly A., Wigle, Tim J., Kuntz, Kevin W., Chesworth, Richard, Pollock, Roy M., Scott, Margaret P., Moyer, Mikel

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 373 KB

english, 2012

3

Developing Novel Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors: Beyond the Butterfly

Anderson, Karen, Basavapathruni, Aravind

Journal:

Current Pharmaceutical Design

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

4

Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase

Juliana Ruiz-Caro, Aravind Basavapathruni, Joseph T. Kim, Christopher M. Bailey, Ligong Wang, Karen S. Anderson, Andrew D. Hamilton, William L. Jorgensen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 124 KB

english, 2006

5

C-2-Aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors

Roger Hunter, Yassir Younis, Clare I. Muhanji, Tanith-lea Curtin, Kevin J. Naidoo, Melissa Petersen, Christopher M. Bailey, Aravind Basavapathruni, Karen S. Anderson

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.34 MB

english, 2008

6

Envelope Variable Region 4 Is the First Target of Neutralizing Antibodies in Early Simian Immunodeficiency Virus mac251 Infection of Rhesus Monkeys

Yeh, W. W., Brassard, L. M., Miller, C. A., Basavapathruni, A., Zhang, J., Rao, S. S., Nabel, G. J., Mascola, J. R., Letvin, N. L., Seaman, M. S.

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

7

[d4U]-butyne-[HI-236] as a non-cleavable, bifunctional NRTI/NNRTI HIV-1 reverse-transcriptase inhibitor

Roger Hunter, Clare I. Muhanji, Ian Hale, Christopher M. Bailey, Aravind Basavapathruni, Karen S. Anderson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

8

Modulation of Human Immunodeficiency Virus Type 1 Synergistic Inhibition by Reverse Transcriptase Mutations †

Basavapathruni, Aravind, Vingerhoets, Johan, de Béthune, Marie-Pierre, Chung, Raymond, Bailey, Christopher M., Kim, Jiae, Anderson, Karen S.

Journal:

Year:

2006

Language:

english

File:

PDF, 296 KB

english, 2006

9

Defining a Molecular Mechanism of Synergy between Nucleoside and Nonnucleoside AIDS Drugs

Basavapathruni, A.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 612 KB

english, 2003

10

ChemInform Abstract: Chiral Synthons via Chloroperoxidase Catalysis

L. P. HAGER, F. J. LAKNER, A. BASAVAPATHRUNI

Journal:

Year:

1999

File:

PDF, 24 KB

1999

11

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

Daigle, S. R., Olhava, E. J., Therkelsen, C. A., Basavapathruni, A., Jin, L., Boriack-Sjodin, P. A., Allain, C. J., Klaus, C. R., Raimondi, A., Scott, M. P., Waters, N. J., Chesworth, R., Moyer, M. P.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.43 MB

english, 2013

12

Probing the Mechanistic Consequences of 5-Fluorine Substitution on Cytidine Nucleotide Analogue Incorporation by HIV-1 Reverse Transcriptase

Ray, A. S., Schinazi, R. F., Murakami, E., Basavapathruni, A., Shi, J., Zorca, S. M., Chu, C. K., Anderson, K. S.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2003

Language:

english

File:

PDF, 302 KB

english, 2003

13

Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target

Waters, Nigel J., Daigle, Scott R., Rehlaender, Bruce N., Basavapathruni, Aravind, Campbell, Carly T., Jensen, Tyler B., Truitt, Brett F., Olhava, Edward J., Pollock, Roy M., Stickland, Kim A., Dovlet

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 1.58 MB

english, 2015

14

Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor

Basavapathruni, Aravind, Olhava, Edward J., Daigle, Scott R., Therkelsen, Carly A., Jin, Lei, Boriack-Sjodin, P. Ann, Allain, Christina J., Klaus, Christine R., Raimondi, Alejandra, Scott, Margaret Po

Journal:

Biopharmaceutics & Drug Disposition

Year:

2014

Language:

english

File:

PDF, 770 KB

english, 2014

15

Envelope Vaccination Shapes Viral Envelope Evolution following Simian Immunodeficiency Virus Infection in Rhesus Monkeys

Basavapathruni, A., Yeh, W. W., Coffey, R. T., Whitney, J. B., Hraber, P. T., Giri, A., Korber, B. T., Rao, S. S., Nabel, G. J., Mascola, J. R., Seaman, M. S., Letvin, N. L.

Journal:

Journal of Virology

Year:

2010

Language:

english

File:

PDF, 3.03 MB

english, 2010

16

Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP

Basavapathruni, Aravind, Gureasko, Jodi, Porter Scott, Margaret, Hermans, William, Godbole, Adarsh, Leland, Peter A., Boriack-Sjodin, P. Ann, Wigle, Tim J., Copeland, Robert A., Riera, Thomas V.

Journal:

Year:

2016

Language:

english

File:

PDF, 354 KB

english, 2016

17

Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase

William L. Jorgensen, Juliana Ruiz-Caro, Julian Tirado-Rives, Aravind Basavapathruni, Karen S. Anderson, Andrew D. Hamilton

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 172 KB

english, 2006

18

Reverse transcription of the HIV-1 pandemic

Basavapathruni, A., Anderson, K. S.

Journal:

The FASEB Journal

Year:

2007

Language:

english

File:

PDF, 428 KB

english, 2007

19

Mechanistic Studies to Understand the Progressive Development of Resistance in Human Immunodeficiency Virus Type 1 Reverse Transcriptase to Abacavir

Ray, A. S., Basavapathruni, A., Anderson, K. S.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 720 KB

english, 2002

20

A Thorough Electrocardiogram Study of Edoxaban, a Novel Factor Xa Inhibitor

Mendell, J., Basavapathruni, R., Swearingen, D., Draves, A., Zhang, G., Morganroth, J.

Journal:

Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 200 KB

english, 2011

21

Mechanism of Action of (-)-(2R,4R)-1-(2-hydroxymethyl-1,3-dioxolan-4-yl)thymine as an anti-HIV agent

Murakami, E., Bao, H., Basavapathruni, A., Bailey, C. M., Du, J., Steuer, H. M. M., Niu, C., Whitaker, T., Anderson, K. S., Otto, M. J., Furman, P. A.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

22

Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis

Robert A. Copeland, Aravind Basavapathruni, Mikel Moyer, Margaret Porter Scott

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 386 KB

english, 2011

23

P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys

A Basavapathruni, W Yeh, R Coffey, J Whitney, P Hraber, A Giri, S Rao…

Journal:

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

24

Probing the Molecular Mechanisms of AZT Drug Resistance Mediated by HIV-1 Reverse Transcriptase Using a Transient Kinetic Analysis †

Ray, Adrian S., Murakami, Eisuke, Basavapathruni, Aravind, Vaccaro, Joseph A., Ulrich, Dagny, Chu, Chung K., Schinazi, Raymond F., Anderson, Karen S.

Journal:

Year:

2003

Language:

english

File:

PDF, 184 KB

english, 2003

25

Bifunctional inhibition of HIV-1 reverse transcriptase: A first step in designing a bifunctional triphosphate

Piao, Dongyuan, Basavapathruni, Aravind, Iyidogan, Pinar, Dai, Guangxiu, Hinz, Wolfgang, Ray, Adrian S., Murakami, Eisuke, Feng, Joy Y., You, Fei, Dutschman, Ginger E., Austin, David J., Parker, Kathl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 871 KB

english, 2013

26

Chiral synthons via chloroperoxidase catalysis

Lowell P. Hager, Frederick J. Lakner, Aravind Basavapathruni

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

1998

Language:

english

File:

PDF, 227 KB

english, 1998

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